The Zetasizer Nano can provide size measurements on samples in the maximum size range from 0.3 nanometers to 10 microns in diameter. Size measurements are carried out by Dynamic Light Scattering (DLS)
The procedure uniquely eliminates electro-osmotic effects while preserving the ability to measure zeta potential distributions.Ħ. M3-PALS provides high sensitivity zeta potential results utilizing optimized analyses with minimal applied voltage in order to minimize the effects of high electric fields on samples. Malvern’s Mixed Mode Measurement was invented and patented for superior accuracy coupled with ease of use. Zeta potential results using the M3-PALS method provides the highest accuracy and sensitivity available in the market. Zeta potential measurements are carried out using Malvern’s patented M3-PALS method
However, it is multifunctional so it can also be used with aqueous media.ĥ. Highly non-polar media like hexane, heptane and toluene can be used as dispersants with this cell. The universal dip cell is solvent-resistant and can be used for both aqueous and non-aqueous samples. The electrophoretic mobility of non-aqueous samples can be measured using the Universal Dip Cell accessory This sample cell combines two highly desired features in that it is able to make zeta potential measurements on samples up to 40 wt% solids while requiring low sample volumes (as little as 150μL of sample).Ĥ. Whether you only have a small volume of sample or a concentrated opaque sample, use the High Concentration-Low Volume cellĪ high concentration zeta potential cell option that uses palladium electrodes and a very small capillary allows for measurement of samples at higher concentrations than previously possible. This method is called a diffusion barrier technique and it protects the protein sample from denaturation by introducing a physical distance between the sample and the electrodesģ. This provides a plug of protein that is far from the electrode surfaces of the zeta potential cell.
A small volume (50μL) of protein is then injected into the bottom of the cell as a plug of sample. A cell is filled with the same buffer that is used as the dispersing medium for the protein sample to be measured. This measurement method uses the standard disposable/reusable capillary zeta potential cells. Measurement of protein samples with a new Diffusion Barrier Method for highly improved results without damaging the protein structure Therefore, it is possible to modify the chemistry of a material substrate and obtain results about the surface activity of surfactants or other formulation materials onto a solid surface.Ģ. The results will provide information about coating surfaces and the interface of a material. This will allow researchers to study the surface of a material and adsorption or desorption processes from that surface. It is now possible to obtain zeta potential measurement of a solid surface using a newly designed cell for the Zetasizer Nano Instrument. Measurement of the zeta potential of a solid surface with the new Surface Zeta Potential Cell